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Type and frequency of toxicity events by grade of severity
| Toxicity | Grade 1 | Grade 2 | Grade 3 | Grade 4 | Total |
|---|---|---|---|---|---|
| Anemia | 9 | 11 | 2 | 0 | 22 |
| Neutropenia | 9 | 6 | 3 | 0 | 18 |
| Thrombocytopenia | 8 | 2 | 0 | 0 | 10 |
| Diarrhea | 7 | 2 | 1 | 0 | 10 |
| Nausea/Vomiting | 4 | 1 | 5 | 0 | 10 |
| Constipation | 4 | 2 | 0 | 0 | 6 |
| Edema | 5 | 2 | 0 | 0 | 7 |
| Neuropathy | 5 | 3 | 1 | 0 | 9 |
| Thromboembolic | 0 | 0 | 0 | 1 | 1 |
| Transaminase | 9 | 0 | 0 | 0 | 9 |
| Fatigue | 11 | 10 | 1 | 0 | 22 |
| Rash | 3 | 2 | 0 | 0 | 5 |
| Dyspnea | 0 | 0 | 1 | 0 | 1 |
| Arrhythmia | 1 | 0 | 0 | 0 | 1 |
