Fig. 1.

Somatic genetic alterations in three oligodendrogliomas identified by whole-genome sequencing. Shown are all mutations identified in three tumors that (i) were localized to the coding regions of exons,( ii) were nonsynonymous, (iii) were absent from dbSNP130 and (iv) had a somatic score >−20. Alterations are coded in greyscale by the type of mutation (deletion, insertion, snp, substitution). The number of alterations range from 8 to 32 variants per sample. All 55 mutations were validated by Sanger sequencing