Figure 1.

Rhodnius prolixus cDNA, deduced protein sequence and predicted gene structure of the serotonin type 2b receptor, Rhopr5HTR2b. (A) Nucleotide and amino acid numbers are denoted on the left and right side of the sequences, respectively. Exon boundaries are denoted by nucleotides in red text. The predicted hydrophobic alpha-helices that form the seven transmembrane domains are outlined by black boxes. Residues predicted as phosphorylation sites exclusively by protein kinase C are highlighted in yellow (Thr₁₂₆, Thr₂₁₈, Ser₃₉₇ and Ser₅₅₉) while exclusive sites for protein kinase A are highlighted in red (Ser₃₆₆, and Ser₅₅₄) and shared sites are highlighted in green (Thr₁₃₁, Thr₂₃₇ and Ser₅₂₅). (B) The Rhopr5HTR2b cDNA identified is produced by six exons and five introns spanning a genomic region of over 80.7 kb.