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Dose-dependent activity of serotonin on semi-isolated dorsal vessel preparations in vitro. (A) Sample traces of various concentrations of serotonin, where the black bar denotes time of application of serotonin to a preparation displaying spontaneous heart beats in saline. (B) Summary of dose-dependent effects of serotonin on the heart bioassay plotted as change in the heart rate (beats/min) from saline control. Data points are means ± standard error (n = 8–12 for each data point).
