Table 2.
Depression severity and intensity, as measured with HDRS-17 and MADRS scales (mean ± sd) and evolution of the inflammatory profile, as measured by hsCRP and fibrinogen levels, according to the depression status over a 9-month follow-up period after an ACS
| D7 | M1 | M3 | M9 | |||||
|---|---|---|---|---|---|---|---|---|
| No Depression 71.3% | Depression 28.7% | No Depression 71.3% | Depression 28.7% | No Depression 71.3% | Depression 28.7% | No Depression 71.3% | Depression 28.7% | |
| MADRS | 5.5 ± 3 | 6.9 ± 4 | 5.7 ± 4 | 13.9 ± 8* | 6.2 ± 4 | 18.2 ± 8** | 5.5 ± 5 | 21.0 ± 8** |
| HDRS-17 | 6.7 ± 3 | 9.2 ± 4 | 9.0 ± 5 | 14.0 ± 7* | 8.6 ± 5 | 17.2 ± 7* | 7.5 ± 5 | 20.1 ± 5** |
| hs-CRP (mg/l) | 8.7 ± 8.0 | 10.1 ± 11.0 | 2.30 ± 2.3 | 3.05 ± 4.2 | 2.12 ± 2.5 | 2.27 ± 3.8 | 2.65 ± 6.4 | 2.46 ± 3.4 |
| Fibrinogen (g/l) | 5.22 ± 1.1 | 5.62 ± 1.2* | 3.97 ± 0.7 | 4.18 ± 1.1 | 3.65 ± 0.6 | 3.62 ± 1.0 | 3.69 ± 0.8 | 4.16 ± 0.8* |
*p values of tests comparing the “No depression” and “Depression” groups (Student’s t test for age, Chi square tests for proportions). *p < 0.05; **p < 0.01.