Table 2. Univariate Associations 24 Hours Prior to Complication Onset.
| Controls (N=125) |
Infection (N=77) |
DCI (N=34) |
Statistic a | P | |
|---|---|---|---|---|---|
| Demographics | |||||
| Age ≥ 53b | 74 (59%) | 51 (66%) | 17 (50%) | 2.66 | 0.26 |
| Women | 82 (66%) | 51 (66%) | 26 (76%) | 1.41 | 0.49 |
| Non-white Ethnicity | 71 (57%) | 52 (68%) | 20 (59%) | 2.17 | 0.34 |
| Clinical Factors | |||||
| Loss of consciousness at ictus | 69 (55%) | 36 (47%) | 15 (45%) | 2.22 | 0.33 |
| Hunt-Hess Grade ≥ 4 | 60 (48%) | 32 (42%) | 13 (38%) | 1.56 | 0.46 |
| Glasgow Coma Scale ≤ 8 | 58 (47%) | 29 (38%) | 9 (26%) | 5.25 | 0.07 |
| APACHE II score - Physiological | 8 (6,13) | 7 (5,11) | 7 (5,9) | 3.77 | 0.02 |
| Fever > 38° C | 40 (32%) | 52 (68%) | 21 (62%) | 26.14 | <0.001 |
| External Ventricular Drain | 56 (45%) | 48 (62%) | 20 (59%) | 6.51 | 0.04 |
| Aneurysm Characteristics | |||||
| Size ≥ 10 mm | 16 (13%) | 9 (12%) | 4 (12%) | 0.08 | 0.96 |
| Clipping Procedure | 37 (30%) | 45 (58%) | 27 (79%) | 29.91 | <0.001 |
| Admission Echocardiogram | |||||
| Ejection Fraction ≤ 40% | 15 (12%) | 16 (21%) | 7 (21%) | 3.21 | 0.20 |
| Any Wall Motion Abnormalities | 17 (14%) | 10 (13%) | 5 (15%) | 0.06 | 0.97 |
| Admission CT | |||||
| Admission Cerebral Edema | 67 (54%) | 48 (62%) | 21 (62%) | 1.59 | 0.45 |
| Hijdra SAH Sum Score ≥15 | 79 (63%) | 44 (57%) | 25 (76%) | 3.84 | 0.15 |
| IVH present | 81 (65%) | 59 (79%) | 21 (64%) | 4.08 | 0.13 |
| ICH present | 22 (18%) | 14 (19%) | 10 (30%) | 2.57 | 0.28 |
| Bicaudate Index ≥16 | 48 (38%) | 44 (62%) | 16 (50%) | 6.35 | 0.04 |
| TCD Flow Velocity | |||||
| Maximum Velocity > 120 cm/sec | 11 (9%) | 13 (17%) | 18 (53%) | 35.38 | <0.001 |
| White Blood Cell Count | |||||
| <4000/mm3 or >12000/mm3 | 13 (10%) | 39 (51%) | 18 (53%) | 46.83 | <0.001 |
| Medications | |||||
| Beta Blockers | 2 (2%) | 5 (6%) | 0 (0%) | 5.18 | 0.08 |
| Vasopressor support | 15 (12%) | 17 (22%) | 11 (32%) | 8.57 | 0.01 |
| Propofol | 12 (10%) | 16 (21%) | 4 (12%) | 5.19 | 0.08 |
| Analgesia and Sedation | 12 (10%) | 11 (14%) | 5 (15%) | 1.31 | 0.52 |
Values are N (%), median (25%, 75%);
a
Chi-square test for dichotomized variables, general linear model for continuous variables;
b
Dichotomized at median age