Fig. 5.

Lack of endogenous Fgfr2b ligands signaling during injury (0–28 dpi) did not lead to increased bleomycin-induced lung injury (28 dpi). A: survival curve. B: relative weight change. C: all DTG mice tested positive for solFgfr2b transcript at 28 dpi. **, Very significant. D: compliance. E–F′: low and high magnification of H/E staining of STG control mice (E and E′) and DTGs fed doxycycline food from 0 to 28 dpi (F and F′). G: quantification of confluent fibrotic areas in H/E stains of left lobes. H: hydroxyproline content of accessory and medial lobes. Scale bars E and F: 2 mm; E′ and F′: 200 μm.