Fig. 5.

Roflumilast increases the rate of ASL height recovery after acute CS exposure. A: graph showing mean ASL height over time, as measured by xz confocal microscopy in HBECs exposed to air and ADO. ■, air; ○, air + adenosine; n = 12. B: mean ASL height over time in HBECs exposed to CS followed by roflumilast ± ADO or vehicle. ■, CS; ●, CS + ADO; ▲, roflumilast; ▼, roflumilast + ADO; n = 12. C: slope of ASL secretion taken from B. Slope shows ASL height recovery after treatment. *P < 0.05; **P < 0.01 vs. CS control.