Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Diagram illustrating the influence of intracellular renin due to internalization or to expression of renin transcript on chemical communication between heart cells. The interaction between renin and pro (renin) receptor occurring inside a cytoplasmic vesicle can induce: the formation of Ang II, and the translocation of PLZF to the nucleus [see Ref. (38)], and consequent generation of oxidative stress through PI3K-Akt pathway with consequent decline of gap junction communication.
