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. 2015 May 19;6:81. doi: 10.3389/fendo.2015.00081

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Copyright © 2015 Beranger, Djedaini, Battaglia, Roux, Scheideler, Heymann, Amri and Pisani.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of OT on body weight, muscle weight, and fat mass in ORX mice. Sham and ORX mice were submitted to daily injections of OT or Ve for 8 weeks starting 2 weeks after surgery. (A) Body and (B) muscle weights were measured at the end of treatment. (C) The volume of white adipose tissue between lumbar vertebra 1 (L1) and the caudal vertebra 4 (C4) was measured using micro-computed tomography. (D,E) Intra-abdominal and subcutaneous adipose tissue areas were measured on one section at the L4/L5 (lumbar vertebra 4 and 5) junction level (n = 12 mice/group). Data are represented as mean ± SEM. (A) p < 0.05 vs. Sham-Ve and (B) p < 0.05 vs. ORX-Ve.