Table 3. Association of SNPs in FGF and FGFR genes with overall survival in ovarian cancer patients.

SNP	Gene	Position	Event (ww/wv/vv)^a	No event (ww/wv/vv)	HR (95% CI)^b	P	Model^c
rs7961824	FGF23	3′ Flanking region	90/47/9	80/76/17	0.55 (0.39–0.78)	0.0008	Dom^d
rs7708357	FGFR4	3′ Flanking region	64/65/17	56/86/31	0.62 (0.44–0.87)	0.0065	Dom^d
rs17102287	FGFR2	Intron	96/45/5	130/39/4	1.61 (1.12–2.31)	0.010	Dom^d
rs641101	FGFR4	5′ Flanking region	71/65/10	72/83/18	0.7 (0.53–0.93)	0.013	Add^d
rs308441	FGF2	Intron	102/39/5	97/66/10	0.63 (0.43–0.91)	0.013	Dom^d
rs167428	FGF2	Intron	82/55/9	77/82/14	0.67 (0.48–0.95)	0.023	Dom^d
rs2981427	FGFR2	Intron	47/75/24	54/81/38	0.59 (0.37–0.93)	0.023	Rec^d
rs17099029	FGF1	3′ UTR	120/23/3	148/25/0	1.71 (1.07–2.72)	0.024	Dom^d
rs7658439	FGF5	5′ Flanking region	131/13/1	164/9/0	1.88 (1.05–3.35)	0.033	Dom^d
rs376618	FGFR4	Exon	82/57/6	93/64/16	0.74 (0.56–0.98)	0.033	Add
rs15608	FGF14	3′ UTR	73/57/14	102/58/12	1.86 (1.05–3.29)	0.033	Rec

ww, homozygous for wild-type allele; wv, heterozygous for variant allele; vv, homozygous for variant allele; OR, odds ratio; UTR, untranslated region.

Adjusted for age, stage, histology, and treatment

Models of inheritance: Add, additive; Dom, dominant; Rec, recessive.

Remained significant for >75% of the 1000 bootstrap resamplings.