Figure 1. Tissue-Resident Macrophages Can Be Distinguished by Expression Patterns.
(A) Schematic for defining the global regulatory elements of tissue-resident macrophages, monocytes, and neutrophils isolated by the gating strategy (Data S1) and analyzed by sequencing data from high-throughput RNA-seq, ChIP-seq, and ATAC-seq. A representative genome browser output is shown.
(B) K-means clustering (K = 11) of 3,348 differentially expressed genes in macrophages (MΦ) and monocytes.
(C) Bar graphs of individual gene expression in arbitrary units (a.u.). Error bars indicate SEM.
See also Figure S1, Table S1, and Experimental Procedures.