Table 4.
The relationship between parameters and survival in patients with mGPS = 0 (n = 213).
| Parameter | Patients | Univariate | Multivariate | ||
|---|---|---|---|---|---|
| N | HR (95% CI) | P value | HR (95% CI) | P value | |
| Age | |||||
| <60/60–69/70–79/≥80 years | 33/71/89/28 | 1.16 (0.98–1.37) | 0.077 | — | |
| Sex | |||||
| Male | 115 | 1 | — | — | — |
| Female | 108 | 0.81 (0.61–1.09) | 0.169 | — | — |
| Centre | |||||
| Aberdeen | 98 | 1 | 0.068 | — | — |
| Fife | 10 | 2.72 (1.40–5.29) | — | — | — |
| Stobhill | 77 | 1.00 (0.72–1.41) | — | — | — |
| Inverclyde | 38 | 1.13 (0.75–1.70) | — | — | — |
| Deprivation (most deprived = 1, least deprived = 5) | |||||
| 1/2/3/4/5 | 68/24/71/39/21 | 0.94 (0.85–1.05) | 0.299 | — | — |
| Smoking history (NS = never smoker, otherwise pack years) | |||||
| NS/<20/20–60/>60 | 21/24/126/37 | 0.93 (0.77–1.12) | 0.467 | — | — |
| Performance status | |||||
| 0/1/2/3/4 | 42/96/60/22/3 | 1.76 (1.47–2.11) | <0.001 | 1.69 (1.39–2.06) | <0.001 |
| Weight loss (% body weight) | |||||
| 0/<5/5–10/>10 | 147/24/12/38 | 1.21 (1.08–1.37) | 0.002 | 1.18 (1.04–1.33) | 0.009 |
| FEV1 (%) | |||||
| >80/80–60/59–40/<40 | 138/31/45/7 | 0.94 (0.80–1.12) | 0.515 | — | — |
| Local symptoms | |||||
| No/yes | 36/127 | 1.38 (0.91–2.09) | 0.124 | — | — |
| Stage | |||||
| NSCLC | |||||
| I/II/IIIa/IIIb/IV | 32/11/7/38/38 | 1.38 (1.25–1.53) | <0.001 | 1.06 (1.01–1.23) | 0.017 |
| SCLC | |||||
| Limited/extensive | 13/21 | 1.05 (0.97–1.14) | 0.228 | — | — |
| Treatment | |||||
| Radical | |||||
| BSC/surgery/RT | 37/26/8 | 0.61 (0.48–0.78) | 0.001 | — | — |
| Palliative | |||||
| Chemo/RT/BSC | 59/27/47 | 1.22 (1.01–1.46) | 0.039 | 1.30 (1.08–1.55) | 0.004 |