Table 4.

Multivariate Cox regression analysis of patient and treatment factors.

		Patients (n)	HR	95% confidence interval		P value (Cox model)
				Lower	Upper
Age at diagnosis	<70 years old	128	Ref.
	≥70 years old	117	1.20	0.84	1.71	0.33
Eastern Cooperative Oncology Group (ECOG) performance status	0, 1	154	Ref.
	2	51	2.41	1.56	3.74	<0.01
	3, 4	21	4.84	2.44	9.58	<0.01
Histology	Epithelial	154	Ref.
	Sarcomatoid	34	2.18	1.33	3.55	<0.01
	Mixed	27	2.10	1.25	3.55	<0.01
Stage	I	84	Ref.
	II	20	1.08	0.57	2.05	0.81
	III	69	1.54	1.03	2.30	0.04
	IV	63	2.04	1.35	3.09	<0.01
Symptoms	Weight loss <5%	156	Ref.
	Weight loss ≥5%	89	1.44	0.98	2.12	0.06
Bloodwork	White blood cell count <8.7	118	Ref.
	White blood cell count ≥8.7	109	1.55	1.08	2.25	0.02
	Platelets ≤400	171	Ref.
	Platelets >400	55	1.64	1.11	2.42	0.01
Extrapleural pneumonectomy	Yes	20	Ref.
	No	225	1.57	0.80	3.08	0.19
Chemotherapy	Yes	139	Ref.
	No	106	2.32	1.59	3.39	<0.01
Radiation therapy	Yes	90	Ref.
	No	155	1.60	1.13	2.27	<0.01