Table 5.
Top 10 differentially expressed lncRNA and protein-coding genes in inflamed ulcerative colitis
| Gene name | Transcript | FC |
|---|---|---|
| Up-regulated lncRNAs | ||
| RP11-731 F5.2 | ENST00000460164.1 | 20.64 |
| MMP12 | ENST00000532855.1 | 17.05 |
| MMP12 | ENST00000326227.5 | 16.54 |
| RP11-465 L10.10 | ENST00000419897.1 | 9.52 |
| KIF9-AS1 | ENST00000429315.2 | 5.75 |
| FAM66D | ENST00000526690.1 | 5.73 |
| SAA2-SAA4 | ENST00000524555.1 | 5.66 |
| CLRN1-AS1 | ENST00000476886.1 | 4.64 |
| RP11-1149O23.3 | ENST00000517774.1 | 4.29 |
| RP5-1028 K7.2 | ENST00000578280.1 | 4.21 |
| Down-regulated lncRNAs | ||
| ANRIL (CDKN2B-AS1) | ENST00000422420.1 | -8.67 |
| ANRIL (CDKN2B-AS1) | ENST00000428597.1 | -8.31 |
| ANRIL (CDKN2B-AS1) | ENST00000585267.1 | -7.06 |
| ANRIL (CDKN2B-AS1) | ENST00000580576.1 | -6.92 |
| ANRIL (CDKN2B-AS1) | ENST00000577551.1 | -6.74 |
| ANRIL (CDKN2B-AS1) | ENST00000581051.1 | -6.72 |
| ANRIL (CDKN2B-AS1) | ENST00000582072.1 | -6.68 |
| PDZK1P2 | ENST00000401008.2 | -6.67 |
| DPP10-AS1 | ENST00000432658.1 | -5.95 |
| ANRIL (CDKN2B-AS1) | ENST00000421632.1 | -5.78 |
| Up-regulated protein-coding genes | ||
| DUOXA2 | NM_207581 | 109.61 |
| CHI3L1 | NM_001276 | 39.71 |
| SAA1 | NM_000331 | 30.67 |
| CXCL1 | NM_001511 | 25.92 |
| MMP7 | NM_002423 | 21.2 |
| SLC6A14 | NM_007231 | 20.52 |
| IGHG3 | ENST00000390551 | 20.14 |
| MMP12 | NM_002426 | 15.76 |
| C4orf7 | NM_152997 | 14.76 |
| CXCL2 | NM_002089 | 11.91 |
| Down-regulated protein-coding genes | ||
| PCK1 | NM_002591 | -15.24 |
| OSTalpha | NM_152672 | -11.33 |
| ANPEP | NM_001150 | -11.02 |
| SLC26A2 | NM_000112 | -10.46 |
| GBA3 | NM_020973 | -9.28 |
| GUCA2A | NM_033553 | -9.22 |
| SLC3A1 | NM_000341 | -9.21 |
| GUCA2B | NM_007102 | -8.84 |
| TMIGD1 | NM_206832 | -8.17 |
| SLC1A7 | NM_006671 | -6.57 |
Top 10 up- and down-regulated lncRNA and protein-coding genes in iUC versus control comparison. The log2 fold change is denoted as FC.