Table 6.
Top 10 differentially expressed genes in inflamed Crohn’s disease versus inflamed ulcerative colitis
| Gene name | Transcript | FC |
|---|---|---|
| Up-regulated lncRNAs | ||
| FLJ42969 | ENST00000514926.1 | 2.6 |
| AC007182.6 | ENST00000455232.1 | 2.42 |
| RP11-542 M13.2 | ENST00000599411.1 | 2.04 |
| RP11-399 F4.4 | ENST00000453998.1 | 1.87 |
| FAM95B1 | ENST00000455995.1 | 1.87 |
| RP3-395 M20.8 | ENST00000432521.2 | 1.69 |
| RP3-395 M20.8 | ENST00000448624.2 | 1.65 |
| OPLAH | ENST00000426825.1 | 1.61 |
| OPLAH | ENST00000534424.1 | 1.61 |
| SPPL2B | ENST00000592738.1 | 1.59 |
| Down-regulated lncRNAs | ||
| AL928742.12 | ENST00000412518.1 | -2.01 |
| RP11-444D3.1 | ENST00000540811.1 | -1.84 |
| AL928742.12 | ENST00000427543.1 | -1.8 |
| FAM25D | ENST00000426412.2 | -1.69 |
| RP11-274 N19.2 | ENST00000515643.1 | -1.64 |
| RP11-838 N2.4 | ENST00000579007.1 | -1.59 |
| RP11-279 F6.3 | ENST00000558941.1 | -1.57 |
| RP11-279 F6.3 | ENST00000559212.1 | -1.55 |
| LINC00524 | ENST00000555860.1 | -1.54 |
| VAV3-AS1 | ENST00000438318.1 | -1.52 |
| Up-regulated protein-coding genes | ||
| C8G | NM_000606 | 2.75 |
| SLC25A34 | NM_207348 | 2.43 |
| UGT1A6 | NM_001072 | 2.25 |
| LRRC66 | NM_001024611 | 2.20 |
| EXOC3L4 | NM_001077594 | 1.95 |
| ANO7 | NM_001001891 | 1.95 |
| GLYCTK | NM_145262 | 1.90 |
| CLEC10A | NM_182906 | 1.89 |
| FAM95B1 | NR_026759 | 1.89 |
| LPIN3 | NM_022896 | 1.87 |
| Down-regulated protein-coding genes | ||
| SERPINB3 | NM_006919 | -3.87 |
| SLC6A14 | NM_007231 | -3.51 |
| GAL | NM_015973 | -2.50 |
| GJB4 | NM_153212 | -2.38 |
| IGHV1-58 | ENST00000390628 | -2.29 |
| CRYM | NM_001888 | -2.28 |
| SLC26A4 | NM_000441 | -2.22 |
| DEFB103B | NM_018661 | -2.22 |
| LAMC2 | NM_005562 | -2.20 |
| TUSC3 | NM_178234 | -2.02 |
Top 10 up- and down-regulated lncRNAs and protein-coding genes in iCD versus iUC. The log2 fold change is denoted as FC.