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. 2015 Apr 30;4(5):886–898. doi: 10.1016/j.stemcr.2015.04.004

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© 2015 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).

PMC Copyright notice

Increased mRNA Expression of Antioxidant and Detoxifying Enzymes in iPSCs

The iPSCs and fibroblasts were screened for the differential expression of factors involved in cellular ROS detoxification by qRT-PCR. mRNA expression in L1 fibroblasts was set as 1. A representative dataset is shown. GAPDH, GAPDH glyceraldehyde-3-phosphate dehydrogenase; ALAS, aminolevulinate synthase; ACTB, beta-actin; GST, glutathione S-transferase; MGST, microsomal GST; GPX, glutathione peroxidase; PRDX, peroxiredoxin; CAT, catalase; GSR, GSH reductase; TXN, thioredoxin; TMX1, thioredoxin-related transmembrane protein 1; TXNIP, thioredoxin-interacting protein; SOD, superoxide dismutase.