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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Bone. 2014 Nov 29;72:92–100. doi: 10.1016/j.bone.2014.11.018

Figure 2. Loss of EP1 protects against ovariectomy-induced bone loss.

Figure 2

Sham or OVX surgeries were performed on 4-month-old EP1−/− and WT mice. Trabecular bone regions in the metaphyseal femur [A] and the vertebral body [D] were examined. [B & E] Bone volume/total volume; [C & F] trabecular number, trabecular spacing, and trabecular thickness quantification of the femur and L4 vertebrae, respectively. N = 5 per group. Statistical analysis was performed using 2-way ANOVA followed by Dunnett’s test. (*) = p < 0.05 v.s. WT sham, ($) = p<0.05 vs KO Sham, (#) = p < 0.05 v.s. WT OVX.