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. 2015 May 14;8:1043–1051. doi: 10.2147/OTT.S70691

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© 2015 Li et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Tyrphostin AG1296 suppresses A375R tumor growth in vivo.

Notes: (A) After inoculation of A375R cells, tyrphostin AG1296 (40 and 80 mg/kg) was injected in to the mice every day. The tumors were measured every other day and tumor volumes are shown. (B) Tyrphostin AG1296 induced apoptosis of A375R tumor cells in vivo examined with TUNEL assay (green), and the nuclei were stained with Hoechst (blue). (C) Tyrphostin AG1296 had no significant cytotoxic effects on body weight of mice during the treatments.