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. Author manuscript; available in PMC: 2015 Sep 27.
Published in final edited form as: Science. 2015 Feb 19;347(6229):1436–1441. doi: 10.1126/science.aaa3650

Fig. 4. Variants in TBK1 and OPTN.

Fig. 4

Dominant not benign variants are shown in TBK1 and OPTN (combined datasets). LoF variants are filled in red, non-synonymous variants are filled in blue, and splice variants are filled in purple. Case variants are shown with red lines, control variants are shown with blue lines, and variants found in both cases and controls are shown with dashed lines.