Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Feb 6;15:31. doi: 10.1186/s12885-015-1019-1

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Noro et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

FISH analysis of the MET gene and immunohistochemical staining for MET protein. Gene copy numbers (GCNs) and amplification of the MET gene were examined by fluorescence in situ hybridization (FISH). (A) FISH negativity was defined as mean MET per cell < 5 copies. (B) High polysomy was defined as 5 copies≦mean MET per cell. (C) Amplification was defined as 2≦MET gene (red)/CEP7q (green) per cell. FISH positivity consisted of high polysomy and amplification. (D) Low level of MET protein expression in lung adenocarcinoma tissues. (E) Moderate level of MET protein expression in lung adenocarcinoma tissues. (F) High level of MET protein expression in lung adenocarcinoma tissues. Bars indicate 100 μm.