Table 2.

Clinicopathologic characteristics of the 35 lung adenocarcinoma cases

			MET gene FISH status
			FISH-negative		FISH-positive		p-value
	Total	%	Total	%	Total	%
Variables	35	100	24	100	11a	100
Age
<65	13	37	9	38	4	36
65≦	22	63	15	63	7	64	1.00
Gender
Male	15	43	12	50	3	27
Female	20	57	12	50	8	73	0.28
Smoking status
Current and former smoker	14	40	10	42	4	36
Never smoker	21	60	14	58	7	63	1.00
Stage
III	4	11	3	13	1	9
IV + Relapse	31	89	21	87	10	91	1.00
EGFR mutation subtype
Exon19 deletion	25	71	19	79	6	55
Exon21 L858R	10	29	5	21	5	46	0.23
Response to Gefitinib
CR + PR	31	89	22	92	9	82
SD + PD	4	11	2	8	2	18	0.57

^aHigh polysomy was observed in 10 patients (28.5%) and amplification was in 1 patients (2.9%) of 35 NSCLC patients.