Skip to main content
. Author manuscript; available in PMC: 2015 May 19.
Published in final edited form as: Cytokine. 2011 Apr 27;55(1):110–115. doi: 10.1016/j.cyto.2011.03.003

Fig. 5.

Fig. 5

VEGFR inhibitors decreases significantly the EF-induced increases in VEGF and IL-8 expression. HUVECs were pretreated with 50 μMVEGFR inhibitor (for both VEGFR1 and VEGFR2) or 100 μM SU1498 (for VEGFR2 only) for 1 h. Then the cells were stimulated by an EF of 200 mV mm−1 for 24 h. Cells that had not been subjected to an EF was used as the control. Culture supernatant was collected and analyzed as described under Section 2. (A and C) VEGF and IL-8 protein levels in the supernatant respectively; (B and D) percent VEGF and IL-8 proteins in culture supernatant respectively. The error bars represent the SE (**p < 0.01). VEGFR inhibitors block the EF-mediated increase in IL-8 protein levels.