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. Author manuscript; available in PMC: 2015 May 19.
Published in final edited form as: Cancer. 2008 May 1;112(9):1905–1911. doi: 10.1002/cncr.23350

TABLE 1. Patient and Tumor Characteristics by HER-2 Status.

All patients
HER-2 negative
HER-2 positive
No.
No.
No.
No. 179 Percent 111 Percent 68 Percent P
Age at diagnosis, y
 Minimum 27 29 27
 Median 51 51 48.5
 Maximum 78 75 78 .3796
Histology
 Other 17 10% 12 11% 5 8%
 Ductal 155 90% 97 89% 58 92% .515
Grade
 1/2 35 20% 25 23% 10 15%
 3 137 80% 82 77% 55 85% .208
ER status
 Negative 111 62% 65 59% 46 68%
 Positive 67 38% 45 41% 22 32% .252
PR status
 Negative 124 70% 70 64% 54 79%
 Positive 53 30% 39 36% 14 21% .032
Lymphovascular invasion
 Negative 34 22% 23 23% 11 20%
 Positive 122 78% 77 77% 45 80% .626
Lymph node classification
 N0 17 10% 11 10% 6 9%
 N1–3 159 90% 99 90% 66 91% .840
Pathologic CR
 No 154 87% 97 88% 57 85%
 Yes 23 13% 13 12% 10 15% .551

ER indicates estrogen receptor, PR, progesterone receptor, CR, complete response.