TABLE 1. Patient and Tumor Characteristics by HER-2 Status.
All patients |
HER-2 negative |
HER-2 positive |
|||||
---|---|---|---|---|---|---|---|
No. |
No. |
No. |
|||||
No. | 179 | Percent | 111 | Percent | 68 | Percent | P |
Age at diagnosis, y | |||||||
Minimum | 27 | 29 | 27 | ||||
Median | 51 | 51 | 48.5 | ||||
Maximum | 78 | 75 | 78 | .3796 | |||
Histology | |||||||
Other | 17 | 10% | 12 | 11% | 5 | 8% | |
Ductal | 155 | 90% | 97 | 89% | 58 | 92% | .515 |
Grade | |||||||
1/2 | 35 | 20% | 25 | 23% | 10 | 15% | |
3 | 137 | 80% | 82 | 77% | 55 | 85% | .208 |
ER status | |||||||
Negative | 111 | 62% | 65 | 59% | 46 | 68% | |
Positive | 67 | 38% | 45 | 41% | 22 | 32% | .252 |
PR status | |||||||
Negative | 124 | 70% | 70 | 64% | 54 | 79% | |
Positive | 53 | 30% | 39 | 36% | 14 | 21% | .032 |
Lymphovascular invasion | |||||||
Negative | 34 | 22% | 23 | 23% | 11 | 20% | |
Positive | 122 | 78% | 77 | 77% | 45 | 80% | .626 |
Lymph node classification | |||||||
N0 | 17 | 10% | 11 | 10% | 6 | 9% | |
N1–3 | 159 | 90% | 99 | 90% | 66 | 91% | .840 |
Pathologic CR | |||||||
No | 154 | 87% | 97 | 88% | 57 | 85% | |
Yes | 23 | 13% | 13 | 12% | 10 | 15% | .551 |
ER indicates estrogen receptor, PR, progesterone receptor, CR, complete response.