TABLE 3. Multivariate Models for Recurrence-free and Overall Survival.
| Hazards ratio |
Lower 95% CI |
Upper 95% CI |
P | |
|---|---|---|---|---|
| Recurrence-free survival | ||||
| Age (continuous) | 0.96 | 0.93 | 0.98 | <.0001 |
| HER-2 status (positive vs negative) | 0.75 | 0.46 | 1.22 | .241 |
| ER status (positive vs negative) | 0.51 | 0.29 | 0.90 | .020 |
| PR status (positive vs negative) | 0.70 | 0.40 | 1.25 | .227 |
| Lymphovascular invasion (yes vs no) | 1.03 | 0.56 | 1.88 | .938 |
| Grade (3 vs 1/2) | 0.92 | 0.49 | 1.71 | .787 |
| Lymph node classification (N1–3 vs N0) | 1.12 | 0.54 | 2.32 | .755 |
| Pathologic CR (yes vs no) | 0.30 | 0.11 | 0.83 | .020 |
| Overall survival | ||||
| Age (continuous) | 0.95 | 0.93 | 0.98 | .0002 |
| HER-2 status (positive vs negative) | 0.56 | 0.34 | 0.93 | .024 |
| ER status (positive vs negative) | 0.51 | 0.29 | 0.88 | .016 |
| PR status (positive vs negative) | 0.72 | 0.41 | 1.25 | .243 |
| Lymphovascular invasion (yes vs no) | 0.59 | 0.31 | 1.10 | .099 |
| Grade (3 vs 1/2) | 1.00 | 0.54 | 1.87 | .992 |
| Lymph node classification (N1–3 vs N0) | 1.49 | 0.72 | 3.08 | .282 |
| Pathologic CR (yes vs no) | 0.34 | 0.12 | 0.95 | .039 |
95% CI indicates 95% confidence interval; ER, estrogen receptor, PR, progesterone receptor, CR, complete response.