Table 3.
Summary of Hierarchical Regression Analysis Predicting Aggressive Behavior in Pooled Subjects (N = 72) and Post Hoc Simple Regression Analysis in Each Group (n = 18)
| All | AN | CN | AA | CA | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Variables |
B (SE B) |
β |
B (SE B) |
Β |
B (SE B) |
β |
B (SE B) |
β |
B (SE B) |
β |
| Step 1 | ||||||||||
| AcbC | 0.71 (0.23) |
0.67** | 0.23 (0.28) |
0.19 | 0.37 (0.19) |
0.46 | 0.13 (0.21) |
0.15 | 0.42 (0.35) |
0.26 |
| AcbSh | −0.99 (0.26) |
−0.81** | 0.12 (0.39) |
0.07 | 0.50 (0.23) |
0.50 | −0.01 (0.24) |
−0.01 | −0.12 (0.51) |
−0.05 |
| BLA | 0.02 (0.34) |
0.01 | 0.48 (0.45) |
0.24 | −0.01 (0.62) |
−0.00 | −0.79 (0.65) |
−0.31 | −0.15 (1.43) |
−0.02 |
| Step 2 | ||||||||||
| AcbC | 0.59 (0.24) |
0.56* | --- | --- | --- | --- | --- | --- | --- | --- |
| AcbSh | −0.78 (0.27) |
−0.64** | --- | --- | --- | --- | --- | --- | --- | --- |
| BLA | 0.05 (0.34) |
0.02 | --- | --- | --- | --- | --- | --- | --- | --- |
| AcbC × AcbSh | 0.00 (0.01) |
0.06 | −0.01 (0.02) |
−0.17 | 0.01 (0.01) |
0.17 | −0.00 (0.01) |
−0.12 | 0.01 (0.02) |
0.05 |
| AcbC × BLA | 0.05 (0.03) |
0.29 | 0.00 (0.04) |
0.01 | −0.04 (0.02) |
−0.37 | −0.02 (0.02) |
−0.22 | 0.05 (0.05) |
0.25 |
| AcbSh × BLA | −0.08 (0.04) |
−0.42* | 0.02 (0.05) |
0.08 | −0.08 (0.04) |
−0.49 | −0.02 (0.04) |
−0.12 | −0.02 (0.05) |
−0.08 |
| Step 3 | ||||||||||
| AcbC | 0.60 (0.24) |
0.56* | --- | --- | --- | --- | --- | --- | --- | --- |
| AcbSh | −0.78 (0.28) |
−0.64** | --- | --- | --- | --- | --- | --- | --- | --- |
| BLA | 0.00 (0.45) |
0.00 | --- | --- | --- | --- | --- | --- | --- | --- |
| AcbC × AcbSh | 0.00 (0.01) |
0.06 | --- | --- | --- | --- | --- | --- | --- | --- |
| AcbC × BLA | 0.04 (0.03) |
0.28 | --- | --- | --- | --- | --- | --- | --- | --- |
| AcbSh × BLA | −0.08 (0.04) |
−0.41 | --- | --- | --- | --- | --- | --- | --- | --- |
| AcbC × AcbSh × BLA | 0.00 (0.00) |
0.02 | 0.00 (0.00) |
0.23 | 0.00 (0.00) |
−0.20 | 0.00 (0.00) |
−0.13 | 0.00 (0.00) |
0.03 |
Note: R2 = 0.22 for Step 1 in all rats; ΔR2 = 0.05 for Step 2 in all rats; ΔR2 = 0.00 for Step 3 in all rats. AcbC = dopamine D2 receptor density in the core of the nucleus accumbens; AcbSh = dopamine D2 receptor density in the shell of the nucleus accumbens; BLA = 5-HT1B receptor density in the basolateral amygdala. AN = acute exposure to non-aggression; CN = chronic exposure to non-aggression; AA = acute exposure to aggression; CA = chronic exposure to aggression.
Age was covaried in all steps.
*
p < 0.05;
**
p < 0.01.