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. Author manuscript; available in PMC: 2016 Jul 1.
Published in final edited form as: Virology. 2015 Apr 7;481:223–234. doi: 10.1016/j.virol.2015.02.023

Figure 3.

Figure 3

Design of anti-HCV group I introns. Displaying I19 targeting U329 (top) and I20 targeting U343 (bottom). Target HCV and intron sequences are displayed in the 5’-3’ and 3’-5’direction, respectively. The intron contains the following components in 5’-3’ direction: EGS, LB, IGS, trans-splicing domain, P10, reconstructed IRES+30nt core sequence, and 3’exon.