Table 2.

Risk of Venous Thromboembolism with Lipid Lowering Therapy (Either Statin or Non-Statin) Compared to No Lipid Lowering Therapy

Model	Lipid Lowering Therapy versus no lipid therapy
Model	Odds Ratio	95% Confidence Interval	P-value

Unadjusted	0.73	(0.55, 0.96)	0.03
Adjusted for^‡:
BMI	0.70	(0.53, 0.93)	0.01
Trauma / fracture	0.75	(0.56, 0.99)	0.05
Hospitalized +/− surgery^†	0.61	(0.44, 0.86)	0.01
Active cancer	0.77	(0.57, 1.04)	0.09
Neurological disease, with leg Paresis	0.72	(0.54, 0.96)	0.03
Pacemaker/ catheter	0.63	(0.47, 0.86)	0.003
Varicose veins	0.75	(0.57, 0.99)	0.04
Nursing home^*^§	0.75	(0.57, 0.99)	0.04
Prior Superficial Thrombosis	0.75	(0.56, 1.00)	0.05
Oral Contraceptives	0.73	(0.55, 0.96)	0.03
Pregnancy/Postpartum	0.73	(0.55, 0.96)	0.03
Estrogen/Progesterone/Oral Contraceptives	0.73	(0.55, 0.97)	0.03
Diabetes	0.70	(0.53, 0.93)	0.01
CHF	0.71	(0.54, 0.95)	0.02
Angina/MI	0.59	(0.44, 0.79)	0.0005
Stroke	0.68	(0.51, 0.91)	0.008
Peripheral Vascular Disease	0.70	(0.53, 0.92)	0.01
Ever Smoker	0.73	(0.55, 0.97)	0.03
Warfarin	0.73	(0.55, 0.96)	0.02
Heparin	0.73	(0.55, 0.97)	0.03
All of the above factors	0.67	(0.43, 1.04)	0.08

^‡

Modeling was done using conditional logistic, however all models were adjusted for age at event or index since the matching was within ± 1 year; there were no missing values.

^†

In hospital or within 92 days of previous hospitalization compared to no hospitalization in the past 92 days. Within the 3 months prior, the hospitalization occurred in the contest of a surgery or an acute medical illness (2 level variable).

All nursing home patients including those in hospital or in hospital in the previous 92 days.

^§

Two cases are missing nursing home confinement data