Skip to main content
. Author manuscript; available in PMC: 2016 Jul 1.
Published in final edited form as: Psychoneuroendocrinology. 2015 Mar 24;57:1–13. doi: 10.1016/j.psyneuen.2015.03.016

Figure 3.

Figure 3

Analyses of the “target list” of 90 genes implicated in PTSD at the pcor<0.10 level which implicate glucocorticoid receptor signaling. A) A plot of the fold-change estimates for the 35 PTSD-associated “target list” genes identified as GR regulated in the dexamethasone stimulation experiment. Fold change estimates from the dexamethasone experiment are presented on the x axis and the fold-change estimates from the comparison of male PTSD cases and controls in the white non-Hispanic discovery sample are presented on the y axis. B) INGENUITY-generated network of interacting genes with glucocorticoid receptor signaling genes/molecules highlighted in purple. The grey shapes indicate genes and molecules from the target list, while open shapes indicate that a gene was added by INGENUITY to increase network connectivity.