Skip to main content
. Author manuscript; available in PMC: 2016 Jun 1.
Published in final edited form as: Biochim Biophys Acta. 2015 Apr 13;1849(6):637–652. doi: 10.1016/j.bbagrm.2015.03.007

Figure 7. Differential co-activator recruitment in response to IL-1β.

Figure 7

A, C, E. 832/13 cells were untreated (NT) or stimulated with 1 ng/mL IL-1β for 15 mins. ChIP assays were used to determine relative occupancy of p65, CARM1, p300 and CBP on the CCL20 proximal promoter (A), and on the CCL2 (C) and COX2 (E) promoters. ***, P < 0.001 vs. NT, **, P < 0.01 vs. NT, *, P < 0.05 vs. NT. B, D, F. 832/13 cells were untreated (NT) or stimulated with 1 ng/mL IL-1β for 15, 30 or 60 mins. ChIP assay of histone H3 dimethylated on Arginine 17 (H3R17me2) is shown at the CCL20 proximal promoter (B), and on the CCL2 (D) and COX2 (F) promoters. *, P < 0.05 vs. NT, #P < 0.1 vs. NT. Data are shown as means ± SEM from 3 individual experiments.