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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: Int J Cancer. 2015 Jan 7;137(3):744–749. doi: 10.1002/ijc.29414

Figure 1.

Figure 1

Dopamine (DA) treatment significantly reduced the growth of (a) orthotopic HT29 colon cancer and (b) subcutaneous lewis lung carcinoma (LLC) tumors as compared to untreated tumors. Tumor angiogenesis was also significantly reduced in dopamine treated (c) HT29 and (d) LLC tumors compared to respective untreated controls. In contrast to sunitinib, dopamine treatment had no significant effect on the diastolic, systolic and mean blood pressures of normal (e) athymic nude and (f) C57/BL6 mice. Results are mean ± SE of three separate experiments; n=13 per group;*P < 0.05 when compared to respective controls.