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. 2015 May 19;10(5):e0123078. doi: 10.1371/journal.pone.0123078

Table 1. General characteristics of the included studies.

Study Population Sample size (IG/CG) Mean age IG/CG (SD) % Female IG/CG Setting (n) Country
Aragonès et al. 2014 [33, 76, 77] Patients with major depression 338 (166/126) 47.5 (15.5) / 47.8 (14.9) 81.0 / 77.2 PCC (20) Spain
Araya et al. 2006 [34] Female patients aged 18–70 with major depression 240 (96/95) 44.1 (12.1) / 42.0 (13.7) 100.0 PCC (3) Chile
Bosmans et al. 2014 [35] Elderly residential home residents at risk of major depression and/or anxiety disorder 185 (93/92) 84.0 (6.7) / 84.0 (6.4) 72.0 / 74.0 Residential homes NL
Donohue et al. 2014 [51, 78, 79] Post-CABG patients with depressive symptoms 189 (90/99) 66.9 (9.0) / 67.1 (11.5) 36.0 / 41.0 PCP USA
Goorden et al. 2013 [36, 80] Sick-listed employees with major depression 126 (65/61) 41.9 (11.4) / 43.4 (11.4) 53.8 / 54.1 Occupational Health Care NL
Green et al. 2014 [50, 81, 82] Patients with major depression 581 (276/305) 45.0 (13.2) / 44.5 (13.4) 73.2 / 70.8 PCP (49) UK
Hay et al. 2012 [20, 37] Low income patients with major depression and diabetes 387 (193/194) Not given 85.5 / 79.8 PCC (2) USA
Katon et al. 2012 [38, 83] Patients with major depression and diabetes and/or CHD 214 (106/108) 57.4 (10.5) / 56.3 (12.1) 48.0 / 56.0 PCC (14) USA
Katon et al. 2005 [39, 84, 85] Patients aged ≥60 with major depression and/or dysthymia 1801 (906/895) 71.0 (7.4) / 71.4 (7.5) 65.0 / 64.0 PCC (18) USA
Liu et al. 2003 [40] Patients with major depression and/or dysthymia 354 (168/186) 57.8 (13.5) / 56.6 (14.2) 95.0 / 96.0 PCC (1) USA
Pyne et al. 2010 [21, 22, 41] Patients with major depression 320 (141/179) 58.8 (11.4) / 60.0 (11.7) 5.0 / 11.0 PCP (89) USA
Rost et al. 2005 [42, 86, 87] Patients with major depression 211 (115/96) 43.1 (14.8) 84.4 PCP (12) USA
Schoenbaum et al. 2001 [43, 88, 89] Patients with major depression 1356 (424+489/ 443) 44.5 (15.5) / 42.2 (13.9) 71.6 / 69.0 PCP (48) USA
Simon et al. 2007 [44, 90, 91] Patients with major depression and diabetes 329 (165/164) 58.0 (12.0) / 57.0 (12.0) 35.0 / 34.0 PCC (9) USA
Simon, Katon et al. 2001 [45, 92] Patients with depressive symptoms 228 (110/109) 47.0 (14.0) 74.0 PCC (4) USA
Simon, Manning et al. 2001 [46] Patients with major depression 407 (218/189) 45.6 (8.6) / 45.4 (9.6) 77.0 / 78.0 PCC (7) USA
van der Weele et al. 2012 [47] Patients aged ≥75 with untreated depressive symptoms 239 (121/118) 80.0 / 80.0 70.0 / 75.0 PCP (67) NL
van't Veer-Tazelaar et al. 2010 [48, 93] Patients aged ≥75 at risk of major depression and anxiety disorder 170 (86/84) 81.8 (3.8) / 81.1 (3.5) 69.8 / 77.4 PCP (33) NL
Von Korff et al. 1998 [13, 49, 52] * Patients with major depression 91 (49/42) 43.2 (15.4) / 42.3 (12.7) 77.5 / 88.1 PCC (1) USA
65 (31/34) 43.1 (9.3) / 44.8 (15.9) 77.4 / 73.5

CABG = Coronary Artery Bypass Graft, CHD = Coronary Heart Disease, IG = Intervention Group, CG = Control Group, PCC = Primary Care Clinic, PCP = Primary Care Practice, NL = the Netherlands, UK = United Kingdom

*Analysis was based on two RCT