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. 2015 Apr 14;11(3):e388–e397. doi: 10.1200/JOP.2014.003293

Table 2.

All-Cause and Colon Cancer–Specific Mortalities and Cost at 12 Months Associated With Patient Sharing per Year

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Analysis All-Cause Mortality*
Colon Cancer–Specific Mortality*
Dollars Saved at 12 Months*
HR 95% CI Sub-HR 95% CI Mean 95% CI
Final Model
Patient sharing as continuous with top coding 0.95 0.92 to 0.97 0.95 0.91 to 0.97 345 −571 to 1,222
Sensitivity Analyses
Varying how patient sharing is modeled
    Patient sharing as continuous without top coding§ 0.95 0.91 to 0.98 0.94 0.90 to 0.97 405 −325 to 1,217
    Upper quartile of patient sharing (compared with lower three quartiles) 0.86 0.82 to 0.89 0.85 0.81 to 0.87 1,047 −998 to 2,009
Varying covariates in adjustment model
    Patient-sharing where oncologist panel and yearly surgical volume are modeled as continuous 0.93 0.89 to 0.95 0.92 0.89 to 0.94 339 −633 to 1,034
    Patient sharing where models additionally adjust for substage 0.95 0.93 to 0.97 0.94 0.92 to 0.97 594 −1,051 to 2,799
    Patient sharing where models additionally adjust for care at one or two hospitals 0.93 0.90 to 0.97 0.93 0.91 to 0.96 331 −789 to 1,205
Varying cost models
    Dollars saved among top 5% of costs NA NA −14,621 −64,193 to 31,497
    Dollars saved at 12 months among only those surviving to 12 months NA NA 1,748 −401 to 3,112
    Dollars saved at 6 months NA NA 629 −104 to 1,145
    Dollars saved at 6 months among only those surviving to 6 months NA NA 416 −218 to 921
Including missing data using multiple imputation
    Patient sharing as continuous with top coding, using missing data 0.94 0.92 to 0.96 0.94 0.91 to 0.96 501 −729 to 1,334

Abbreviations: HR, hazard ratio; NA, not applicable.

*

Estimates are fully adjusted for all patient, provider, and hospital characteristics listed in Table 1 (except substage unless otherwise noted) as well as diagnosis year and SEER site.

Patients in top 5% of costs are excluded unless otherwise specified.

Estimates report change for each additional patient shared per year, ranging from one patient and top coded at eight. Thus, for example, all-cause mortality and colon cancer–specific mortality decreased by 6% for each additional patient shared.

§

Estimates report change for each additional patient shared per year, ranging from one to 15 patients.

Sample restricted to those diagnosed from 2004 onward, for whom these data were available.