Figure 8.

Organ of Corti supporting cell density remains stable after DT injection in DTR mice. Supporting cells (Sox2⁺ cells) were quantified in the apical turn of experimental (DTR + DT) and control (WT injected with DT, DTR injected with saline, WT injected with saline) animals at 8 and 70 dpi using the nonbiased random sampling described in the Materials and Methods. Each data value represents the mean ± SEM. Controls were grouped together because there were no reliable differences in numbers of Sox2-labeled cells. Note the absence of significant changes in support cell density after DT injection.