Figure 5.

Relationship between ΔBMI and amygdala response to the smell of palatable food. Predicted correlations (ROI analysis) between ΔBMI and BLA response to F > Ol at the hungry scan that interact with genotype in BLA with peak at x, y, z = 27, −1, −20 (A) and SFA with peak at x, y, z = 30, −1, −17 (C). Scatterplots show the relationship between ΔBMI and parameter estimates at the peak voxel. Color bars depict t-values. Histograms show group differences in the relationship between ΔBMI and brain response to F > Ol Hungry in BLA (B) and SFA (D). Bootstrapping was used to depict the observed sample distribution of the correlation coefficient separately for A1+ and A1−. Density on the y-axis reflects the likelihood of observing a particular correlation coefficient (x-axis) and is higher if estimated correlations within groups are more homogenous. Lesser distribution overlap corresponds to stronger group differences.