Figure 9.

Relationship between ΔBMI and caudate response to the taste of palatable food. A, Predicted correlation (ROI analysis) between ΔBMI and caudate response to M > T at hungry scan that interacts by genotype, with statistically significant cluster in caudate with peak at x, y, z = 18, 20, −5. Scatterplot shows the relationship between ΔBMI and parameter estimates at the peak voxel in that region. Color bars depict t-values. B, Histogram shows group differences in the relationship between ΔBMI and caudate response to M > T Hungry. Bootstrapping was used to depict the observed sample distribution of the correlation coefficient separately for A1+ and A1−. Density on the y-axis reflects the likelihood of observing a particular correlation coefficient value (x-axis) and is higher if estimated correlations within groups are more homogenous. Lesser distribution overlap corresponds to stronger group differences.