Table 4.
Haplotype distribution of IL-10 promoter gene (-1082G/A, -819T/C, and -512C/A) in T2D patients considering complications and comorbidities.
| T2D complications/comorbidities | Haplotypes | p a | p b | p c | |||
|---|---|---|---|---|---|---|---|
| ACC% | ATA% | GCC% | |||||
| Retinopathy | Yes (n = 66) | 31.07 | 34.08 | 34.08 | 0.778 | 0.563 | 0.778 |
| No (n = 36) | 34.86 | 29.03 | 35.98 | ||||
|
| |||||||
| Nephropathy | Yes (n = 80) | 32.52 | 33.11 | 33.73 | 0.832 | 0.750 | 0.916 |
| No (n = 20) | 32.58 | 29.92 | 37.42 | ||||
|
| |||||||
| Neuropathy | Yes (n = 42) | 29.77 | 38.08 | 30.94 | 0.670 | 0.300 | 0.550 |
| No (n = 60) | 34.22 | 28.28 | 37.44 | ||||
|
| |||||||
| Hypertension | Yes (n = 94) | 34.06 | 30.30 | 35.62 | 0.418 | 0.204 | 0.418 |
| No (n = 8) | 12.71 | 55.79 | 24.54 | ||||
|
| |||||||
| Dyslipidemia | Yes (n = 96) | 32.36 | 32.22 | 34.82 | 1.000 | 1.000 | 1.000 |
| No (n = 6) | 34.02 | 32.46 | 32.54 | ||||
|
| |||||||
| BMI | <30 (n = 44) | 28.54 | 37.36 | 32.82 | 0.480 | 0.344 | 0.825 |
| ≥30 (n = 58) | 35.36 | 28.43 | 36.19 | ||||
BMI (body mass index): Kg/m2.
p < 0.05 was considered statistically significant.
p a: ACC versus (ATA + GCC).
p b: ATA versus (ACC + GCC).
p c: GCC versus (ACC + ATA).