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Paricalcitol inhibits aldosterone-mediated activation of ERK and STAT-1 pathway. HK2 cells were preincubated with paricalcitol (12 μmol/L) for 48 hours before stimulation with 1 μmol/L Aldo for 15 min. Figure (a) shows a representative experiment and in (b) quantification of p-ERK and p-STAT1 expressed as mean ± SEM of 3 independent experiments. * P < 0.05 versus control. # P < 0.05 versus Aldo.
