Table 3.
SNPs | Groups | Additive model | Dominant model | Recessive model | |||
---|---|---|---|---|---|---|---|
P c | OR (95 % CI) | P c | OR (95 % CI) | P c | OR (95 % CI) | ||
rs2736340 | PM | 0.015 | 0.71 (0.57–0.89) | 0.049 | 0.70 (0.54–0.91) | 0.157 | 0.47 (0.25–0.91) |
DM | 0.133 | 0.82 (0.69–0.97) | 0.142 | 0.78 (0.63–0.97) | 1.405 | 0.76 (0.49–1.19) | |
PM + DM | 7.43 × 10 −3 | 0.78 (0.67–0.91) | 0.016 | 0.75 (0.62–0.91) | 0.239 | 0.66 (0.44–0.98) | |
rs7812879 | PM | 0.047 | 0.73 (0.58–0.92) | 0.138 | 0.73 (0.55–0.96) | 0.222 | 0.45 (0.21–0.95) |
DM | 0.204 | 0.82 (0.68–0.99) | 0.155 | 0.78 (0.62–0.97) | 2.539 | 0.82 (0.50–1.33) | |
PM + DM | 0.021 | 0.79 (0.67–0.92) | 0.032 | 0.76 (0.63–0.92) | 0.545 | 0.68 (0.44–1.06) | |
rs13277113 | PM | 0.05 | 0.75 (0.61–0.93) | 0.150 | 0.74 (0.57–0.96) | 0.234 | 0.54 (0.30–0.97) |
DM | 0.109 | 0.81 (0.69–0.97) | 0.089 | 0.77 (0.62–0.95) | 1.705 | 0.80 (0.53–1.21) | |
PM + DM | 0.012 | 0.79 (0.68–0.92) | 0.021 | 0.76 (0.63–0.91) | 0.365 | 0.70 (0.49–1.02) | |
rs2618479 | PM | 0.138 | 0.77 (0.62–0.96) | 0.391 | 0.78 (0.60–1.02) | 0.300 | 0.51 (0.26–1.00) |
DM | 0.226 | 0.83 (0.69–0.99) | 0.098 | 0.77 (0.62–0.95) | 4.324 | 0.92 (0.59–1.44) | |
PM + DM | 0.044 | 0.81 (0.69–0.94) | 0.043 | 0.77 (0.64–0.93) | 1.220 | 0.77 (0.51–1.15) | |
rs2254546 | PM | 0.182 | 0.78 (0.62–0.98) | 0.300 | 0.76 (0.58–1.00) | 0.846 | 0.61 (0.32–1.18) |
DM | 0.995 | 0.88 (0.74–1.05) | 0.498 | 0.82 (0.66–1.03) | 5.882 | 1.01 (0.64–1.58) | |
PM + DM | 0.206 | 0.84 (0.72–0.99) | 0.140 | 0.80 (0.66–0.97) | 2.819 | 0.86 (0.57–1.30) | |
rs2248932 | PM | 0.959 | 0.85 (0.68–1.07) | 2.871 | 0.91 (0.70–1.18) | 0.189 | 0.44 (0.21–0.93) |
DM | 2.076 | 0.92 (0.77–1.10) | 1.440 | 0.88 (0.71–1.09) | 5.822 | 1.01 (0.64–1.59) | |
PM + DM | 0.961 | 0.89 (0.76–1.05) | 1.346 | 0.89 (0.74–1.07) | 1.721 | 0.80 (0.52–1.21) |
Bold values are statistically significant (P < 0.05) (corrected for multiple comparisons by the Bonferroni adjustment test)
PM polymyositis, DM dermatomyositis, OR odds ratio, CI confidence interval, P c P value corrected by Bonferroni method