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. 2015 Apr 7;62(2):153–162. doi: 10.1007/s12026-015-8646-0

Table 3.

Analysis of the six SNPs based on three genetic models

SNPs Groups Additive model Dominant model Recessive model
P c OR (95 % CI) P c OR (95 % CI) P c OR (95 % CI)
rs2736340 PM 0.015 0.71 (0.57–0.89) 0.049 0.70 (0.54–0.91) 0.157 0.47 (0.25–0.91)
DM 0.133 0.82 (0.69–0.97) 0.142 0.78 (0.63–0.97) 1.405 0.76 (0.49–1.19)
PM + DM 7.43 × 10 −3 0.78 (0.67–0.91) 0.016 0.75 (0.62–0.91) 0.239 0.66 (0.44–0.98)
rs7812879 PM 0.047 0.73 (0.58–0.92) 0.138 0.73 (0.55–0.96) 0.222 0.45 (0.21–0.95)
DM 0.204 0.82 (0.68–0.99) 0.155 0.78 (0.62–0.97) 2.539 0.82 (0.50–1.33)
PM + DM 0.021 0.79 (0.67–0.92) 0.032 0.76 (0.63–0.92) 0.545 0.68 (0.44–1.06)
rs13277113 PM 0.05 0.75 (0.61–0.93) 0.150 0.74 (0.57–0.96) 0.234 0.54 (0.30–0.97)
DM 0.109 0.81 (0.69–0.97) 0.089 0.77 (0.62–0.95) 1.705 0.80 (0.53–1.21)
PM + DM 0.012 0.79 (0.68–0.92) 0.021 0.76 (0.63–0.91) 0.365 0.70 (0.49–1.02)
rs2618479 PM 0.138 0.77 (0.62–0.96) 0.391 0.78 (0.60–1.02) 0.300 0.51 (0.26–1.00)
DM 0.226 0.83 (0.69–0.99) 0.098 0.77 (0.62–0.95) 4.324 0.92 (0.59–1.44)
PM + DM 0.044 0.81 (0.69–0.94) 0.043 0.77 (0.64–0.93) 1.220 0.77 (0.51–1.15)
rs2254546 PM 0.182 0.78 (0.62–0.98) 0.300 0.76 (0.58–1.00) 0.846 0.61 (0.32–1.18)
DM 0.995 0.88 (0.74–1.05) 0.498 0.82 (0.66–1.03) 5.882 1.01 (0.64–1.58)
PM + DM 0.206 0.84 (0.72–0.99) 0.140 0.80 (0.66–0.97) 2.819 0.86 (0.57–1.30)
rs2248932 PM 0.959 0.85 (0.68–1.07) 2.871 0.91 (0.70–1.18) 0.189 0.44 (0.21–0.93)
DM 2.076 0.92 (0.77–1.10) 1.440 0.88 (0.71–1.09) 5.822 1.01 (0.64–1.59)
PM + DM 0.961 0.89 (0.76–1.05) 1.346 0.89 (0.74–1.07) 1.721 0.80 (0.52–1.21)

Bold values are statistically significant (P < 0.05) (corrected for multiple comparisons by the Bonferroni adjustment test)

PM polymyositis, DM dermatomyositis, OR odds ratio, CI confidence interval, P c P value corrected by Bonferroni method