Figure 6. Genetic reduction of arrestin-1 or GRK1 expression does not alter S → A responses.
(A) Representative SPRs in S → A/Arr1+/− rods. (B) Average single S → A responses across cells with either normal (black) or lowered (cyan) arrestin-1 concentration. (C) Response durations in all cells with either normal (black) or lowered (cyan) arrestin-1 concentration. Pooled distributions are indistinguishable (p > 0.05, Kruskal–Wallis analysis of variance, corrected for multiple comparisons). (D–F) Comparison of S → A and S → A/GRK1+/− (magenta) responses and response durations. Pooled distributions are indistinguishable (p > 0.05, Kruskal–Wallis analysis of variance). (G) Median response durations with reduced arrestin-1 or GRK1 in individual S → A rods.