Table 1. The LysR-family OxyR-type peroxide-sensing transcriptional regulators.

Redox sensor	Organism	Signal	Redox-sensing mechanism	Regulon genes	Regulon functions	References
OxyR	Escherichia coli	H2O2 H2O2 NO GSSG	C199*-C208 Intramolecular disulfide Cys199-SOH Cys199-SNO Cys199-SSG	ahpCF katG fur dps mntH sufABCDE trxC grxA gor dsbG hemH oxyR fhuF flu uxuAB gntP	peroxiredoxin catalase Fe-uptake repressor miniferritin Mn-uptake Fe-S cluster assembly thioredoxin glutaredoxin GSH reductase Cys-SOH reduction ferrochelatase LysR-type regulator Fe 3+ reductase antigen 43 outer membrane protein mannonate hydrolase gluconate permease	Storz et al, 1990b Zheng et al, 1998 Choi et al, 2001 Kim et al, 2002
OxyS	Mycobacterium tuberculosis	H2O2	C25* peroxide sensing	katG	catalase	Domenech et al, 2001 Li & He, 2012
OxyR	Deinococcus radiodurans	H2O2	C210*-SOH	katE drb0125 feoB dps mntH	catalase Iron(III) dicitrate- uptake Fe2+ uptake miniferritin Mn uptake	Chen et al, 2008
OxyR	Corynebacterium glutamicum	H2O2	C206* and C215 conserved	katA dps, ftn cydABCD hemH cg1292 sufABCDE proP oxyR sufR ripA	catalase miniferritins cytochrome bd oxidase ferrochelatase flavin- monooxygenase Fe-S-cluster assembly proline-ectoine transporter LysR-type regulator FeS-cluster regulator regulator of iron- proteins	Teramoto et al, 2013 Milse et al, 2014