Table I. Characteristics of CLL Patients at the Time of Hodgkin Lymphoma Diagnosis.
Characteristic | N (%) | |
---|---|---|
Number of patients | 26 | |
Median age, years (range) | 67 (45–88) | |
Male | 21 (81) | |
Median WBC, ×109/L (range) | 7.8 (1.3–87.3) | |
Median HB, g dL−1(range) | 11 (7.2–13) | |
Median PLT, ×109/L (range) | 220.5 (53–627) | |
Median LDH, U L−1(range) | 249 (133–658) | |
Median creatinine, mg dL−1 (range) | 1 (0.6–2.1) | |
Median albumin, g dL−1(range) | 3.5 (2.6–4.2) | |
Ann Arbor stage | I | 0 |
II | 10 (38) | |
III | 3 (11) | |
IV | 11 (42) | |
Undetermined | 2 (8) | |
Epstein–Barr virus statusa | Positive | 6 (67) |
Negative | 3 (33) | |
Not done | 17 | |
Prior CLL therapy before HL diagnosis | No | 9 (35) |
Yes | 17 (65) | |
Purine analog containing regimen | 13 (50) | |
Therapy administered for of HL | ABVD | 16 (61) |
MOPP/ABV hybrid | 3 (11) | |
BCVPP | 2 (8) | |
CVPP | 1 (4) | |
VP | 1 (4) | |
Unknown | 3 (11) |
Performed clinically on select patients.
Abbreviations used: WBC; white cell count; HB: hemoglobin; PLT; platelet; LDH; lactate dehydrogenase; ABVD: doxorubicin, bleomycin, vinblastine and dacarbazine; MOPP/ABV hybrid: mechlorethamine, vincristine, procarbazine, and prednisone (MOPP) followed by doxorubicin, bleomycin and vinblastine (ABV); BCVPP: carmustine, cyclophosphamide, vinblastine, pro-carbazine, and prednisone; CVPP: chlorambucil, vincristine, procarbazine and prednisone; VP: vinblastine and prednisone.