Figure 3.

Synergy and antagonism between nitrate, (per)chlorate and respiratory intermediates. Isobolograms are shown for Desulfovibrio alaskensis G20 inhibition by nitrate and (per)chlorate in combination with each other and respiratory intermediates nitrite, nitric oxide and chlorate. A FICI (Materials and methods) was calculated for each pair of compounds. FICI >2 implies antagonism, FICI<0.5 implies synergism. (a) Perchlorate and nitrate, (b) chlorate and nitrate, (c) chlorate and perchlorate, (d) perchlorate and nitrite, (e) perchlorate and nitric oxide, (f) nitrate and chlorite.