Table 1.

Anthropometric, clinical and laboratory parameters in examined patients (M ± SD)

Parameters	Control	p1	p2	NAFLD with normal transaminases	NAFLD with elevated transaminases	p3	p
	(n = 28)			(n = 37)	(n = 26)
Age, years	53.57 ± 7.16	-	-	53.27 ± 8.39	51.5 ± 10.92	-	NS
Duration of T2D, years	5.0 ± 2.81	-	-	5.97 ± 3.88	8.54 ± 5.57	-	NS
BMI, kg	31.15 ± 3.0	0.028	<0.001	34.46 ± 5.64	40.35 ± 5.63	<0.001	<0.001
ALT, U	25.03 ± 7.26	NS	<0.001	28.93 ± 6.15	64.96 ± 14.99	<0.001	<0.001
AST, U/L	23.91 ± 6.11	NS	<0.001	26.6 ± 5.71	55.8 ± 11.91	<0.001	<0.001
FPI, μIU/ml	11.21 ± 3.58	0.001	<0.001	18.27 ± 8.14	20.61 ± 8.56	NS	<0.001
FPG, mmol/l	7.80 ± 1.41	-	-	8.67 ± 3.25	9.48 ± 3.14	-	NS
HOMA-IR	3.86 ± 1.41	<0.001	<0.001	6,86 ± 3.21	8.23 ± 2.85	NS	<0.001
TC, mmol/l	5.68 ± 0.68	0.004	<0.001	6.24 ± 0.72	6.56 ± 0.62	NS	<0.001
TG, mmol/l	1.83 ± 0,45	0,018	<0,001	2,65 ± 1,2	3,36 ± 1,55	NS	<0,001
VLDL-C, mmol/l	0.82 ± 0.2	0.005	<0.001	1.25 ± 0.59	1.39 ± 0.63	NS	<0.001
HDL-C, mmol/l	1.66 ± 0.25	0.001	<0.001	1.43 ± 0.24	1.2 ± 0.26	0.002	<0.001
LDL-C, mmol/l	3.18 ± 0.6	0.047	<0.001	3.61 ± 0.69	4.07 ± 0.78	0.034	<0.001

p - the difference between all study groups calculated using one-way ANOVA

p 1-3 - for pairwise comparisons used Bonferroni Posthoc test

p1 - the difference between the control and normal transaminases groups

p2 - the difference between the control and elevated transaminases groups

p3 - the difference between normal and elevated transaminases groups