Table 1.
System | Causes of troponin elevation |
Cardiovascular | Acute aortic dissection |
Arrhythmia | |
Medical ICU patients | |
Hypotension | |
Heart failure | |
Apical ballooning syndrome | |
Cardiac inflammation | |
Endocarditis, myocarditis, pericarditis | |
Hypertension | |
Infiltrative disease | |
Amyloidosis, sarcoidosis, hemochromatosis, scleroderma | |
Left ventricular hypertrophy | |
Myocardial injury | Blunt chest trauma |
Cardiac surgeries | |
Cardiac procedures | |
Ablation, cardioversion, percutaneous intervention | |
Chemotherapy | |
Hypersensitivity drug reactions | |
Envenomation | |
Respiratory | Acute PE |
ARDS | |
Infectious/immune | Sepsis/SIRS |
Viral illness | |
Thrombotic thrombocytopenic purpura | |
Gastrointestinal | Severe GI bleeding |
Nervous system | Acute stroke |
Ischemic stroke | |
Hemorrhagic stroke | |
Head trauma | |
Renal | Chronic kidney disease |
Endocrine | Diabetes |
Hypothyroidism | |
Musculoskeletal | Rhabdomyolysis |
Integumentary | Extensive skin burns |
Inherited | Neurofibromatosis |
Duchenne muscular dystrophy | |
Klippel-Feil syndrome | |
Others | Endurance exercise |
Environmental exposure | |
Carbon monoxide, hydrogen sulfide |
GI: Gastrointestinal; ICU: Intensive care unit; PE: Pulmonary embolus; ARDS: Acute respiratory distress syndrome; SIRS: Systemic inflammatory response syndrome.