Table 2.
Groups | Inclusion criteria for each specific miRNA | Based on samples | miRNA targets |
---|---|---|---|
High RR | in vitro Cqmean CSF – Cqmean MD < ±2 and in vitro SDCSF and SDMD both < 1 | 6-13 | 63 |
6-13 | |||
Low RR | in vitro Cqmean MD - Cqmean CSF > 4 and in vitro SDCSF < 1 | 6-13 | 53 |
6-13 | |||
Indetermined RR | Criteria not fulfilled | 6-13 | 173 |
Not present | Not detected in any samples | 6-13 | 465 |
Criteria for categorization of 754 screened miRNAs according to their relative recovery in microdialysate from a catheter with a membrane cut-off value of 20 kDa.
RR, relative recovery; Cqmean CSF, mean cycle quantification of the specific miRNA in sample 10-13, Table 1; Cqmean MD, mean cycle quantification of the specific miRNA in sample 6-9, Table 1; SDCSF, standard deviation of cycle quantification of the specific miRNA in sample 10-13, Table 1; SDMD, standard deviation of cycle quantification of the specific miRNA in sample 6-9, Table 1.