Table 4.
Summary of the major study findings
DNA methylation | Gene expression change in response to the TSST | |
---|---|---|
SLC6A4 expression: LL > S-group | ||
Early life stress ↑ | LINE-1 methylation: S-group ↔ LL ↑ | SLC6A4 expression: S-group ↓ LL ↔ |
F3 methylation: S-group ↑ LL ↔ | ||
Chronic stress ↑ | LINE-1 methylation: S-group ↔ LL ↑ | F1 methylation correl w/ NR3C1 expression: S-group ↑ LL ↔ |
F1 methylation: S-group ↑ LL ↔ |
Note. Arrows pointing up or down indicate significantly increased or decreased methylation/expression, respectively. Sideway arrows indicate no significant change.