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. 2015 Mar 14;10:30. doi: 10.1186/s13023-015-0249-2

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© Tazi et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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The estimated cumulative incidence of lung function deterioration during the study. The overall lung function corresponds to a decrease of at least 15% in FEV₁, FVC, and/or DL_CO. FEV₁ = forced expiratory volume in 1 second; FVC = forced vital capacity; DL_CO = diffusion capacity for carbon monoxide.