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. 2015 Mar 17;18(6):pyv017. doi: 10.1093/ijnp/pyv017

Figure 7.

Figure 7.

A2A receptor blockade is associated with a reduction in basolateral amygdala (BLA) pyramidal cell intrinsic excitability. (A) Relationship of action potential responses to depolarizing current steps under standard recording conditions (open circles) and in the presence of the A2A receptor antagonist ZM-241385 (250nM, closed circles) (*, F ZM (1, 35)=4.840, P=.0345, 2-way RM ANOVA; n=30 for baseline, 7 for ZM-241385). (B) Representative voltage responses to current steps of increasing magnitude recorded from BLA pyramidal neurons under standard recording conditions and in the presence of the A2A receptor antagonist, ZM-241385. Traces in the presence of ZM-241385 are the same as those used in Figure 6.