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. 2015 May 12;13:153. doi: 10.1186/s12967-015-0503-3

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© Xu et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Immunohistochemical staining of NIPBL in lung adenocarcinoma. The overall immunohistochemical staining scores could range from 0 to 12. An overall staining score of ≥6 was considered to be high expression of NIPBL protein, score of 0–5 was considered as low expression. Low level of expression of NIPBL in lung adenocarcinoma sample: (A) Absence of nuclear NIPBL expression, overall staining score is 0, (B) overall staining score is 1–2. High level expression of NIPBL in lung adenocarcinoma samples: (C) overall staining score is 6, (D) overall staining score is 8, (E) and (F) overall staining score are 12. Original magnification: ×200.